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Evolution of High-Intensity Basal Ganglia Lesions on T1-Weighted MR in Neurofibramotisis Type 1 AJNR 17:755-760, Terada,H.A.,et al, 1996 See this aricle in Pubmed Article Abstract The foci of prolonged T2 relaxation in the basal ganglia appear to evolve in a manner similar to the foci of T2 prolongation in the white matter of the posterior fossa.However,the corresponding foci of short T1 in the basal ganglia may evolve with a different time course.In some patients,the foci of short T1 develop at a later time than the T2 prolongation and progress;these foci of short T1 do not appear to regress over periods as long as 90 months.Possible causes of the T1 shortening are remyelination and calcification.

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